Maître de conférence à l’Université de Poitiers, HDR

SFA, Biochimie Biologie Moléculaire

 

Publications à partir de 2011

 

El-Seedy A, Pellerin L, Page G, Ladevèze V. Identification of Intron Retention in the Slc16a3 Gene Transcript Encoding the Transporter MCT4 in the Brain of Aged and Alzheimer-Disease Model (APPswePS1dE9) Mice. Genes (Basel). 2023;14(10):1949. doi: 10.3390/genes14101949. PMID: 37895298; PMCID: PMC10606527.

EL SEEDY A, BOTROS M.H., PAGE G., Ladevèze V. Allelic variants on SLC6A2023 neurotransmitter gene and their relationship with personality traits scales in Egyptian Athletes.  Arch. Mol. Biol. Genet. 2023, 2(1):9-19

Farhat R, EL SEEDY A, Pasquet MC, Corbani S, Megarbané A, Kitzis A, Ladevèze V. Three complex alleles of CFTR gene identified in Lebanese, Egyptian and French population and their potential impact on splicing. Cell Mol Biol (Noisy-le-grand). 2022, 68(4):52-59.

Al Alam C, RIDA F, Farhat R, Ladevèze V. Correlation between ARV1 mutation and Early Infantile Epileptic Encephalopathy: a second case Worldwide. Acta Scientific Clinical Case Reports 2021, 2:2:13-18.

Farhat R, Pasquet MC, Corbani S, Megarbané A, Kitzis A, Ladevèze V. Is Phoenicia the Origin of the N1303K CFTR Mutation? Int J Rare Dis Disord 2019, 2:006. Volume 2 Issue 1.

El-Seedy AS, Shafiek H, Kitzis A, Ladevèze V.  2017. CFTR Gene Mutations in the Egyptian Population: Current and Future Insights for Genetic Screening Strategy. Front Genet., 8:37. doi: 10.3389/fgene.2017.00037. eCollection 2017.

Farhat R, El-Seedy A, Norez C, Talbot H, Pasquet MC, Adolphe C, Kitzis A, Ladevèze V. Complexity of phenotypes induced by p.Asn1303Lys-CFTR correlates with difficulty to rescue and activate this protein. Cell Mol Biol. 2017 Nov 30;63(11):106-110. doi: 10.14715/cmb/2017.63.11.18. PMID: 29208182

Farhat R, El-Seedy A, Sari AIP, Norez C, Pasquet MC, Becq F, Kitzis A, Ladevèze V. In cellulo analyses of the p.Val322Ala mutation on the CFTR protein conformation and activity. C R Biol. 2017 Aug 4. pii: S1631-0691(17)30100-2. doi: 10.1016/j.crvi.2017.06.00

Ladeveze V, Farhat R, El Seedy A and Kitzis A, 2016, Multi-Functional Consequences of a Single Mutation of CFTR of the Importance to Analyze Mutations by Functional Tests Single Cell Biol. 5:2. http://dx.doi.org/10.4172/2168-9431.1000142

El-Seedy A, Pasquet MC , Shafiek H, Morsi T, Kitzis A, Ladevèze V, 2016, Cystic Fibrosis Transmembrane  Conductance Regulator (CFTR) gene mutations in North Egyptian population: implications for the genetic diagnosis in Egypt. Cell. Mol. Biol. 2016, 62 (13): 21-28. ISSN: 1165-158X doi: 10.14715/cmb/2016.62.13.5

Farhat R, Puissesseau G, El-Seedy A, Pasquet M-C, Adolphe C, Corbani S, Megarbane A, Kitzis A, Ladeveze V. 2015. N1303K (c.3909C>G) Mutation and Splicing: Implication of Its c.[744-33GATT(6); 869+11C>T] Complex Allele in CFTR Exon 7 Aberrant Splicing, BioMed Research International, vol. 2015, Article ID 138103, 8 pages, 2015. doi:10.1155/2015/138103.

El-Seedy A, Girodon E, Norez C, Pajaud J, Pasquet M-C, De Becdelievre A, Bienvenu T, Des Georges M, Cabet F, Lalau G, Bieth E, Blayau M, Becq F, Kitzis A, Fanen P, Ladeveze V, 2012. CFTR mutation combinations producing frequent complex alleles with different clinical and functional outcomes. Human Mutation, 33(11):1557-1565. Highlight video Demande du journal Human Mutation (youtube)

Ladeveze V, Chaminade N, Lemeunier F, Periquet G, Aulard S, 2012. General survey of hAT transposon superfamily with highlight on hobo element in Drosophila. Genetica, 140 7-9:375-392.

El-Seedy A, Pasquet M-C, .Bienvenu T, Bieth E, Audrezet M-P, Kitzis A, Ladeveze V, 2013. Consequences of partial duplications of the human CFTR gene on CF diagnosis: mutations or ectopic variations. J. of cystic fibrosis;12(4):407-410.

El-Seedy A, Farhat R, Pasquet M-C, Kitzis A, Ladeveze V, 2014. Minigene analysis of the c.743+40A>G intronic variant in the CFTR gene. Health, 6:1352-1360.

 

Revue à partir de 2011

Sarrouilhe D, Ladeveze V, 2012. When the curtain goes up on spinophilin’s tumor suppressor function. Med Sci (Paris). 2012 Jan;28(1):26-28. doi: 10.1051/medsci/2012281009

Sarrouilhe D, Ladeveze V, 2014. The tumour suppressor function of the scaffolding protein spinophilin. Atlas Genet Cytogent Oncol Haematol. Free online version URL : http://AtlasGeneticsOncology.org/Deep/SpinophilinID20133.html

Communications colloques européens et/ou nationaux

Farhat R, El-Moussaoui K, Pasquet M-C, Adolphe C, Bieth E, Kitzis A, Ladeveze V, 2012. Etude de la mutation c.3903G>T dans la population libanaise et son impact sur l’épissage et la protéine. 13ème colloque des jeunes chercheurs en mucoviscidose, Paris. (*)

El-Seedy A, Pasquet M.C, .Bienvenu T, Bieth E, Audrezet Mp, Kitzis A, Ladeveze V. Consequences of partial duplications of the human CFTR gene on CF diagnosis: mutations or ectopic variations. 35th European Cystic Fibrosis Conference, Dublin. (Irlande). J. of cystic fibrosis, 11 :sup1, S16-WS8.4. (°)

Farhat R, El-Seedy A, El-Moussaoui K, Pasquet M.C, Adolphe C, Sermetgaudelus I, Kitzis A, Ladeveze V. Co-implication of the 5’ and 3’ regions of CFTR exon 10 in its alternative splicing : prediction to pathology. 35th European Cystic Fibrosis Conference, Dublin. (Irlande). J. of cystic fibrosis, 11 :sup1, S16-WS8.3. (°)

Farhat R, Puissesseau G, Pasquet Mc, Adolphe C, Kitzis A, Ladeveze V. Evolution of CFTR exon 10 and duplications in primates. 36^th European Cystic Fibrosis Conference, Lisbonne (Portugal). J of Cystic Fibrosis, 12:1, WS21.5 S44.

Farhat R, Puissesseau G, Pasquet Mc, Adolphe C, Megarbane A, Kitzis A, Ladeveze V, 2013. Detection of a novel complex allele c.[869+11C>T;3909C>G] in CFTR gene. 36^th European Cystic Fibrosis Society, Lisbonne (Portugal).J of Cystic Fibrosis, 12:1, S50.

El-Seedy A, Pasquet M-C, Shafiek H, El-Komy M, Kitzis A, Ladeveze V. 2013. Cystic Fibrosis in Egypt: New mutational detection of the CFTR gene in patients from Alexandria, Northern Egypt. J of Cystic Fibrosis, 12:1, S53.

Farhat R, El-Seedy A, Sari Aip, Pasquet Mc, C. Adolphe C, Kitzis A, Ladeveze V. 2014. In vivo and in silico analyses of impact of the p.Val322Ala mutation on CFTR protein in a Brittany family. European Human Genetics Conference, Milan

FARHAT R, CORBANI C, MEGARBANE A, KITZis A, Ladevèze V., 2018. Multi-biomolecular analyses of CFTR mutations in individual genetic backgrounds for personalized management of Cystic Fibrosis disease Lebanese Association for the Advancement of Science (LAAS), Liban.FARHAT R, EL-SEEDY A, CORBANI S, Mégarbané A, KITZis A, Ladevèze V., 2020. Is Phoenician the origin N1303K CFTR mutation? 43^rd European Cystic Fibrosis Conference, Lyon (France). J of Cystic Fibrosis, 19:2, P006 S56. (en visioconférence).

EL SEEDY A, BOTROS M.H., PAGE G., Ladevèze V, 2022. Allelic variants on SLC6A3 neurotransmitter gene and their relationship with personality traits scales in Egyptian Athletes. Journée scientifique de la SFR FED 4026, Tours.

EL SEEDY A, Ladevèze V., 2023. Exemple de deux transporteurs de la famille SLC et leurs impacts en santé.  Conférence IFR Biologie Santé, Poitiers.